Variable Strength of Translational Selection Among 12 Drosophila Species
نویسندگان
چکیده
منابع مشابه
Variable strength of translational selection among 12 Drosophila species.
Codon usage bias in Drosophila melanogaster genes has been attributed to negative selection of those codons whose cellular tRNA abundance restricts rates of mRNA translation. Previous studies, which involved limited numbers of genes, can now be compared against analyses of the entire gene complements of 12 Drosophila species whose genome sequences have become available. Using large numbers (613...
متن کاملSubstitution rates in Drosophila nuclear genes: implications for translational selection.
The relationships between synonymous and nonsynonymous substitution rates and between synonymous rate and codon usage bias are important to our understanding of the roles of mutation and selection in the evolution of Drosophila genes. Previous studies used approximate estimation methods that ignore codon bias. In this study we reexamine those relationships using maximum-likelihood methods to es...
متن کاملEvolution of Regulatory Sequences in 12 Drosophila Species
Characterization of the evolutionary constraints acting on cis-regulatory sequences is crucial to comparative genomics and provides key insights on the evolution of organismal diversity. We study the relationships among orthologous cis-regulatory modules (CRMs) in 12 Drosophila species, especially with respect to the evolution of transcription factor binding sites, and report statistical eviden...
متن کاملVariable rates of evolution among Drosophila opsin genes.
DNA sequences and chromosomal locations of four Drosophila pseudoobscura opsin genes were compared with those from Drosophila melanogaster, to determine factors that influence the evolution of multigene families. Although the opsin proteins perform the same primary functions, the comparisons reveal a wide range of evolutionary rates. Amino acid identities for the opsins range from 90% for Rh2 t...
متن کاملPhylogenetic Relationships among DROSOPHILA LONGICORNIS, DROSOPHILA PROPACHUCA and DROSOPHILA PACHUCA, a Triad of Sibling Species.
Drosophila longicornis, D. propachuca and D. pachuca comprise a triad of sibling species. They are morphologically indistinguishable, sympatric forms that, under laboratory conditions, are capable of exchanging genes through the production of fertile F(1) females. However, we have no evidence for introgressive hybridization in nature. The chromosomal constitution of our strains indicates that t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genetics
سال: 2007
ISSN: 1943-2631
DOI: 10.1534/genetics.107.070466